SCHEMBL22876258

SCHEMBL22876258

CC1(C)c2ccccc2-c2cc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5cccc6oc7ccc(-c8ccc9ccc%10ccccc%10c9c8)cc7c56)cc4)n3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.34
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 4/20 0.34
HSD17B10 Q99714 4/20 0.34
TSHR P16473 4/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
KMT2A Q03164 4/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22876217 0.97 KDM4E (0.34) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL19802063 0.96 CASP3 (0.34) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL22876489 0.96 PIM1 (0.34) L3MBTL1CASP3SENP7SENP6PLA2G2A
SCHEMBL19802746 0.95 KDM4E (0.33) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL22876551 0.94 KDM4E (0.33) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL22876256 0.94 MAPK1 (0.35) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL19802751 0.94 CASP3 (0.33) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL19802737 0.92 CASP3 (0.34) MAPTKDM4EALDH1A1HPGDTSHR
SCHEMBL22876246 0.92 KDM4E (0.33) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL22876254 0.91 KDM4E (0.34) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed