SCHEMBL22876995

SCHEMBL22876995

CCCC1CCC(C2CC=C(c3ccc(F)c(C(F)(F)F)c3F)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909344 0.88 TLR4 (0.34) TLR4
SCHEMBL2909350 0.88 TLR4 (0.34) TLR4
SCHEMBL14494608 0.88 TLR4 (0.34) TLR4
SCHEMBL22876996 0.86 TAS1R3 (0.30)
SCHEMBL26697883 0.86 TAS1R3 (0.30)
SCHEMBL20797108 0.85 TLR4 (0.33) TLR4
SCHEMBL20808303 0.85 TLR4 (0.33) TLR4
SCHEMBL22877033 0.84 TLR4 (0.31) TLR4
SCHEMBL7668264 0.82 TLR4 (0.34) TLR4
SCHEMBL4400181 0.82 TLR4 (0.34) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119120038-A Liquid crystal medium, liquid crystal display device containing same and compound 默克专利股份有限公司 2024-12-13 CN disclosed
CN-114144498-B Liquid crystal medium, liquid crystal display device containing same and compound 默克专利股份有限公司 2024-09-10 CN disclosed
EP-3994234-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-02-21 EP disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-20220267676-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2022-08-25 US disclosed
EP-3994234-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS Merck Patent GmbH (DE) 2022-05-11 EP disclosed
CN-114144498-A Liquid crystal medium, liquid crystal display containing same and compound 默克专利股份有限公司 2022-03-04 CN disclosed
WO-2021004868-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2021-01-14 WO disclosed