Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656287 | 1.00 | HRH3 (0.42) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27902165 | 0.98 | HRH3 (0.41) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27792525 | 0.98 | HRH3 (0.41) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL29107081 | 0.98 | HRH3 (0.41) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27499872 | 0.98 | HRH3 (0.41) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27656273 | 0.98 | HRH3 (0.41) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL24688643 | 0.98 | HRH3 (0.40) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL3160023 | 0.98 | HRH3 (0.40) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL14127444 | 0.98 | HRH3 (0.40) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL14127405 | 0.96 | DNM1 (0.41) | HRH3L3MBTL1MAPTMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007277-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC DISEASE STATES AND CANCER | PURDUE RESEARCH FOUNDATION (US) | 2021-01-14 | — | — | WO | disclosed |