SCHEMBL22878124

SCHEMBL22878124

CN1CCC2CN(I)CCC21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.33
L3MBTL3 Q96JM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22878182 1.00 HRH3 (0.33) HRH3L3MBTL3
SCHEMBL22878174 1.00 HRH3 (0.33) HRH3L3MBTL3
SCHEMBL24368781 0.88 L3MBTL3 (0.37) L3MBTL3
SCHEMBL23690636 0.84 HRH3 (0.34) HRH3L3MBTL3
SCHEMBL25001495 0.84
SCHEMBL23220719 0.84 HRH3 (0.37) HRH3
SCHEMBL12605039 0.77 HRH3 (0.37) HRH3L3MBTL3
SCHEMBL17285876 0.77 HRH3 (0.37) HRH3L3MBTL3
SCHEMBL12880921 0.77 HRH3 (0.37) HRH3L3MBTL3
SCHEMBL15946756 0.75 HRH3 (0.32) HRH3L3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022087008-A1 TERTIARY CARBOXAMIDE COMPOUNDS VIVACE THERAPEUTICS, INC. (US) 2022-04-28 WO disclosed
EP-3145929-B1 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS HOFFMANN LA ROCHE (CH) 2021-01-13 EP disclosed