Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 5/20 | 0.69 |
| ▸ | RUNX1 | Q01196 | 9/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831265 | 0.96 | CBFB (0.65) | CBFBRUNX1ACHETRPV1 | |
| SCHEMBL179106 | 0.90 | CBFB (0.84) | CBFBRUNX1TRPV1 | |
| SCHEMBL19831439 | 0.85 | CBFB (0.53) | CBFBRUNX1ACHETRPV1 | |
| SCHEMBL24245908 | 0.85 | CBFB (0.69) | CBFBRUNX1TRPV1 | |
| SCHEMBL19831264 | 0.84 | CBFB (0.51) | CBFBRUNX1ACHETRPV1 | |
| SCHEMBL19831263 | 0.84 | CBFB (0.70) | CBFBRUNX1TRPV1 | |
| SCHEMBL179114 | 0.84 | CBFB (0.70) | CBFBRUNX1TRPV1 | |
| SCHEMBL19831268 | 0.84 | CBFB (0.70) | CBFBRUNX1TRPV1 | |
| SCHEMBL24950162 | 0.82 | CBFB (0.65) | CBFBRUNX1TRPV1 | |
| SCHEMBL126350 | 0.80 | CBFB (0.66) | CBFBRUNX1ACHETRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180004-B1 | CANCER THERAPEUTICS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-01-06 | — | — | EP | disclosed |