SCHEMBL2287884

SCHEMBL2287884

CCCCCC(S)N=C=O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
OPRM1 P35372 1/20 0.34
FDPS P14324 4/20 0.34
GPR84 Q9NQS5 5/20 0.33
CA1 P00915 2/20 0.33
FFAR1 O14842 1/20 0.33
LAP3 P28838 2/20 0.32
TP53 P04637 1/20 0.32
LCK P06239 1/20 0.32
PPARD Q03181 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
LMNA P02545 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5572964 0.98 MAPT (0.44) MAPTFDPSGPR84FFAR1LAP3
SCHEMBL27830625 0.78 NAAA (0.40) MAPTOPRM1FDPSLMNA
SCHEMBL112561 0.77 MAPT (0.39) MAPTOPRM1FDPSGPR84CA1
SCHEMBL164412 0.76 MAPT (0.42) MAPTFDPSGPR84FFAR1LAP3
SCHEMBL18324263 0.76 MAPT (0.42) MAPTFDPSGPR84CA1FFAR1
SCHEMBL10439694 0.76 MAPT (0.42) MAPTFDPSGPR84FFAR1LAP3
SCHEMBL2564972 0.76 MAPT (0.42) MAPTFDPSGPR84CA1FFAR1
SCHEMBL21722662 0.76 MAPT (0.42) MAPTFDPSGPR84CA1FFAR1
SCHEMBL21722514 0.76 MAPT (0.42) MAPTFDPSGPR84CA1FFAR1
SCHEMBL21722523 0.76 MAPT (0.42) MAPTFDPSGPR84CA1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640900-A Preparation method of thiourethane optical material KOC SOLUTION CO LTD 2015-05-20 CN claimed
CN-109071756-B Polymer polyol modified flexible foams prepared with DMC-catalyzed polyols 科思创有限公司 2022-04-15 CN disclosed
CN-106220813-B Sulphur urethane system's optical material and its manufacturing method 可奥熙搜路司有限公司 2019-08-30 CN disclosed
CN-105968409-B Thio epoxy base system optical material polymerism synthetic and thio epoxy base system optical material manufacturing method 可奥熙搜路司有限公司 2019-07-30 CN disclosed
CN-109575217-A Polymerizable composition for optical material SKC株式会社 2019-04-05 CN disclosed
CN-108276543-A Glass lens polythiol compositions SKC株式会社 2018-07-13 CN disclosed
CN-107667126-A Thioopoxy-based ultrahigh-refractive-index optical resin composition and preparation method of thioepoxy-based optical material 可奥熙搜路司有限公司 2018-02-06 CN disclosed
CN-107548409-A The preparation method of thio epoxy base system optical material and thio epoxy base system polymerizable composition for optical material 可奥熙搜路司有限公司 2018-01-05 CN disclosed
CN-104662012-B The preparation method of the keeping method of episulfide compound and the thio epoxiess optical material using above-mentioned episulfide compound 可奥熙搜路司有限公司 2017-04-05 CN disclosed
CN-106220813-A Sulfur urethane system's optical material and manufacture method thereof 可奥熙搜路司有限公司 2016-12-14 CN disclosed
CN-104662012-A Method for storing episulfide compound and method for preparing thioepoxy-based optical material using said episulfide compound KOC SOLUTION CO LTD 2015-05-27 CN disclosed
CN-104640900-A Preparation method of thiourethane optical material KOC SOLUTION CO LTD 2015-05-20 CN disclosed
CN-103534288-B A foam composition and its uses thereof MAS RES AND INNOVATION PVT LTD 2015-04-08 CN disclosed
CN-104321308-A Novel method for preparing polythiol compound and polymeric composition for optical material comprising same KOC SOLUTION CO LTD 2015-01-28 CN disclosed
EP-2516495-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-Chemie GmbH (DE) 2012-10-31 EP disclosed
WO-2011085775-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2011-07-21 WO disclosed
CN-1286883-C Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS INC (JP) 2006-11-29 CN disclosed
CN-1239619-C Polythioalcohol, polymerizable compsn. resin and lens and process for preparing thio-alcohol compound MITSUI CHEMICALS INC (JP) 2006-02-01 CN disclosed
CN-1596276-A Polymerizable composition comprising novel sulfur-containing cyclic compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS INC (JP) 2005-03-16 CN disclosed
CN-1317515-A Polythioalcohol, polymerizable compsn. resin and lens and process for preparing thio-alcohol compound MITSUI CHEMICALS INC (JP) 2001-10-17 CN disclosed