SCHEMBL22880321

SCHEMBL22880321

CC(=O)C1(OC(=O)c2cccc3ccccc23)CC=C(C)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37
NR4A3 Q92570 1/20 0.37
PLK1 P53350 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
TLR2 O60603 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
CDC25A P30304 1/20 0.35
CDC25C P30307 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601124 1.00 CDC25B (0.40) CDC25BPOLBGAAKMT2AALDH1A1
SCHEMBL22880599 0.83 CASP3 (0.39) POLBGAAKMT2AALDH1A1KDM4E
SCHEMBL22880595 0.82 CDC25B (0.40) CDC25BPOLBGAAKMT2AALDH1A1
SCHEMBL29414439 0.82 CDC25B (0.40) CDC25BPOLBGAAKMT2AALDH1A1
SCHEMBL22880623 0.80 TSHR (0.38) GAAKMT2AALDH1A1NPC1RAB9A
SCHEMBL22880624 0.80 TSHR (0.38) GAAKMT2AALDH1A1NPC1RAB9A
SCHEMBL22880270 0.80 TSHR (0.38) GAAKMT2AALDH1A1NPC1RAB9A
SCHEMBL22880322 0.79 NPC1 (0.40) ALDH1A1KDM4ENPC1RAB9AHRH3
SCHEMBL29600881 0.79 NPC1 (0.40) ALDH1A1KDM4ENPC1RAB9AHRH3
SCHEMBL22880612 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174245-B Synthesis method of non-racemized cyclohexene 巴斯夫公司 2024-05-10 CN disclosed
CN-114174245-A Synthetic method of non-racemic cyclohexene 巴斯夫公司 2022-03-11 CN disclosed
WO-2021007141-A1 PROCESS FOR THE SYNTHESIS OF NON-RACEMIC CYCLOHEXENES BASF CORPORATION (US) 2021-01-14 WO disclosed