Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16381772 | 0.82 | TYR (0.63) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL15943011 | 0.82 | HCAR2 (0.61) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL18653116 | 0.80 | ESR1 (0.51) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL15483131 | 0.80 | HDAC1 (0.54) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL16588259 | 0.79 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL13883759 | 0.79 | F3 (0.64) | TYRHSD11B1CYP2D6CYP2C9F3 | |
| SCHEMBL1055352 | 0.77 | HCAR2 (0.65) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL27688186 | 0.77 | HCAR2 (0.65) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL1055350 | 0.77 | HCAR2 (0.65) | HDAC1HDAC3HDAC4HDAC2HDAC6 | |
| SCHEMBL14319658 | 0.76 | HDAC1 (0.51) | HDAC1HDAC3HDAC4HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760647-A1 | NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE | Mochida Pharmaceutical Co., Ltd. (JP) | 2021-01-06 | — | — | EP | disclosed |