Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12086479 | 0.81 | NPC1 (0.56) | HDAC1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11283267 | 0.81 | F3 (0.57) | LMNASMN1; SMN2MAOBMAPTHTT | |
| SCHEMBL11283271 | 0.81 | F3 (0.57) | LMNASMN1; SMN2MAOBMAPTHTT | |
| SCHEMBL9353385 | 0.79 | TDP1 (0.59) | LMNASMN1; SMN2MAOBMAPTHTT | |
| SCHEMBL9353382 | 0.79 | TDP1 (0.59) | LMNASMN1; SMN2MAOBMAPTHTT | |
| SCHEMBL765933 | 0.79 | HCAR2 (0.59) | HDAC1LMNASMN1; SMN2MAOBMAPT | |
| SCHEMBL309763 | 0.79 | HCAR2 (0.59) | HDAC1LMNASMN1; SMN2MAOBMAPT | |
| Bicarbonate SCHEMBL867321 | 0.78 | HCAR2 (0.57) | HDAC1LMNASMN1; SMN2MAOBMAPT | |
| Hydrochloric Acid SCHEMBL11763321 | 0.78 | HCAR2 (0.57) | HDAC1LMNASMN1; SMN2MAOBMAPT | |
| SCHEMBL6836595 | 0.78 | LMNA (0.56) | LMNASMN1; SMN2MAOBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414797-B1 | HEPATITIS C VIRUS POLYMERASE INHIBITORS WITH A HETEROBICYLIC STRUCTURE | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-01-02 | — | — | EP | disclosed |