SCHEMBL22883255

SCHEMBL22883255

CC1(C)O[C@@H]2[C@@H](CO)C[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHCY P23526 8/20 0.64
ADORA2B P29275 2/20 0.64
PI4K2A Q9BTU6 2/20 0.62
PI4KA P42356 1/20 0.62
PI4K2B Q8TCG2 1/20 0.62
PI4KB Q9UBF8 1/20 0.62
ADORA2A P29274 2/20 0.51
SLC28A1 O00337 1/20 0.51
SLC28A2 O43868 1/20 0.51
RXFP1 Q9HBX9 1/20 0.50
ADORA3 P0DMS8 1/20 0.48
ADORA1 P30542 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31756504 1.00 AHCY (0.64) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL14520301 1.00 AHCY (0.64) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL31756651 1.00 AHCY (0.64) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL26811312 1.00 AHCY (0.64) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL26811459 0.90 PI4KA (0.55) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL26811445 0.90 PI4KA (0.55) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL31756696 0.90 PI4KA (0.55) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL16424887 0.89 AHCY (0.60) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL5319686 0.87 PI4KA (0.47) AHCYADORA2BPI4K2API4KAPI4K2B
SCHEMBL17889809 0.87 PI4KA (0.47) AHCYADORA2BPI4K2API4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230061-A2 SARS-COV-2 NSP14 METHYLTRANSFERASE INHIBITORS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2023-11-30 WO disclosed
US-20210009630-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS JANSSEN PHARMACEUTICA NV (BE) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009630-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS STING1, CGAS, IFNAR1 AHCY 2783/4885ADORA2B 38/4885PI4K2A 2018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.