Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 19/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962127 | 1.00 | CAPN1 (0.55) | CAPN1CTSSTACR3 | |
| SCHEMBL29961440 | 0.89 | CAPN1 (0.54) | CAPN1CTSS | |
| SCHEMBL22886642 | 0.89 | CAPN1 (0.54) | CAPN1CTSS | |
| SCHEMBL20028416 | 0.88 | CAPN1 (0.56) | CAPN1CTSSTACR3 | |
| SCHEMBL21854047 | 0.85 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL21854026 | 0.85 | CAPN1 (0.53) | CAPN1CTSS | |
| SCHEMBL21854359 | 0.85 | CAPN1 (0.57) | CAPN1CTSS | |
| SCHEMBL20027499 | 0.85 | CAPN1 (0.57) | CAPN1CTSS | |
| SCHEMBL20027883 | 0.84 | CAPN1 (0.52) | CAPN1CTSS | |
| SCHEMBL21854099 | 0.84 | CAPN1 (0.52) | CAPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112703188-A | Method for treating liver fibrosis using calpain inhibitor | 布莱德治疗公司 | 2021-04-23 | — | — | CN | disclosed |
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPERTICS INC (US) | 2021-01-14 | — | — | US | disclosed |
| CN-112204014-A | Calpain modulators and therapeutic uses thereof | 布莱德治疗公司 | 2021-01-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | CAPN1 3/4885CTSS 177/4885TACR3 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.