SCHEMBL2288892

SCHEMBL2288892

CCC1(C(=O)Cl)C(C)C1(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5513888 1.00 TDP1 (0.31) TDP1
SCHEMBL5509512 0.81
SCHEMBL8649051 0.81
SCHEMBL17180610 0.79
SCHEMBL12304838 0.76
SCHEMBL7624073 0.74 LMNA (0.36)
SCHEMBL9639872 0.67
SCHEMBL7024899 0.67
SCHEMBL11506243 0.66
Hydrochloric Acid SCHEMBL9639862 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6157499-A None JP disclosed
EP-1773124-B1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE BAYER CROPSCIENCE AG (DE) 2012-08-22 EP disclosed
US-8008484-B2 Use of sulfonanilides as agricultural and horticultural fungicide BAYER CROPSCIENCE AG (DE) 2011-08-30 US disclosed
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide BAYER CROPSCIENCE AG (DE) 2007-09-20 US disclosed
EP-1773124-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE Bayer CropScience Aktiengesellschaft (DE) 2007-04-18 EP disclosed
US-7205331-B2 Fungicidal carboxamides BASARAB GREGORY STEVEN 2007-04-17 US disclosed
US-7135585-B2 Fungicidal carboxamides BASARAB GREGORY STEVEN 2006-11-14 US disclosed
US-20060178425-A1 FUNGICIDAL CARBOXAMIDES BASARAB GREGORY S 2006-08-10 US disclosed
US-20060025472-A1 FUNGICIDAL CARBOXAMIDES BASARAB GREGORY S 2006-02-02 US disclosed
WO-2006008159-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE BAYER CROPSCIENCE AG (DE) 2006-01-26 WO disclosed
US-6642392-B1 Pyrrole derivatives BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2003-11-04 US disclosed
US-6500986-B1 RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES BAYER AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
US-6441044-B1 CROP PROTECTION AGENT BASF AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
US-6387692-B1 REACTING RACEMIC AMINE WITH AN ESTER IN PRESENCE OF LIPASE FROM CANDIDA ANTARTICA AND DILUNET, SEPARATING (S)-AMINE FROM ACYLATED (R)-AMINE, THEN TREATING ACYLATED (R)-AMINE WITH ACID OR BASE TO FREE (R)-AMINE BAYER AKTIENGESELLSCHAFT (DE) 2002-05-14 US disclosed
US-6251947-B1 CERTAIN N-(ARYLPROPYL), N-(ARYLOXYETHYL), AND N-(ARYLALLYL)-CARBOXAMIDES, THEIR AGRICULTURALLY SUITABLE SALTS USED AS FUNGICIDE TO CONTROL PLANT DISEASE BY APPLYING AN EFFECTIVE AMOUNT ON THE PLANT BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2001-06-26 US disclosed
US-6187582-B1 REACTING RACEMIC AMINE AND ESTER IN PRESENCE OF LIPASE FROM CANDIDA ANTARCTICA AND DILUENT, SEPARATING MIXTURE OF (S)-AMINE, SEPARATING THE ACYLATED (R)-AMINE, THEN OPTIONALLY DEACYLATING THE (R)-AMINE BY TREATMENT WITH AN ACID OR BASE BAYER AKTIENGESELLSCHAFT (DE) 2001-02-13 US disclosed
US-5885787-A Process for preparing optically active amines BAYER AKTIEGESELLSCHAFT (DE) 1999-03-23 US disclosed
US-5773656-A Process for the preparation of optically active 1-aryl-alkylamines BAYER AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
JP-H06157499-A N-@(3754/24)1-SUBSTITUTED ETHYL)-2,2-DICHLOROCYCLOPROPANE CARBOXAMIDE DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE KUMIAI CHEM IND CO LTD 1994-06-03 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide CBR3, CYP51A1, CBR1 TDP1 3863/4885
US-20060178425-A1 FUNGICIDAL CARBOXAMIDES CBR3, CBR1, CYC1 TDP1 877/4885
US-20060025472-A1 FUNGICIDAL CARBOXAMIDES CBR3, CBR1, CYC1 TDP1 954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.