SCHEMBL22889455

SCHEMBL22889455

c1ccc(-c2nc(-c3cccc(-c4cc5ccc(-c6ccccc6-c6ccccc6)cc5c5ccccc45)c3)nc(-c3cccc4c3oc3ccccc34)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
GGPS1 O95749 1/20 0.38
MAPT P10636 7/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
POLB P06746 2/20 0.37
NPSR1 Q6W5P4 1/20 0.36
PRKDC P78527 3/20 0.36
PTGES2 Q9H7Z7 1/20 0.36
TSHR P16473 3/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 3/20 0.35
HSD17B10 Q99714 2/20 0.35
MAPK1 P28482 1/20 0.35
PLA2G10 O15496 1/20 0.34
PLA2G2A P14555 1/20 0.34
PLA2G4A P47712 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21304235 0.98 ALOX5 (0.48) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL22889183 0.97 ALOX5 (0.45) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL21304538 0.97 ALOX5 (0.45) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL22889456 0.97 ALOX5 (0.45) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL21304229 0.94 ALOX5 (0.47) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL21304342 0.94 ALOX5 (0.44) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL21304230 0.93 ALOX5 (0.45) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL21304766 0.92 ALOX5 (0.45) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL22889250 0.92 ALOX5 (0.47) ALOX5GGPS1MAPTALDH1A1KDM4E
SCHEMBL22889386 0.92 ALOX5 (0.49) ALOX5GGPS1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11765972-B2 Compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-19 US disclosed
US-11765972-B2 Compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-19 US disclosed
US-20210009527-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009527-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, RPS4Y1, AR ALOX5 3163/4885GGPS1 3177/4885MAPT 2178/4885
US-11765972-B2 Compound and organic electroluminescence device using the same AR, OR10J3, RPS4Y1 ALOX5 3071/4885GGPS1 3231/4885MAPT 2233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.