Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228918 | 1.00 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4550132 | 1.00 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL16634046 | 0.99 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL16634043 | 0.99 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL230615 | 0.97 | CHRM3 (0.42) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL231279 | 0.97 | CHRM3 (0.44) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL230614 | 0.97 | CHRM3 (0.42) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL231280 | 0.97 | CHRM3 (0.44) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL229890 | 0.97 | CHRM3 (0.42) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL229889 | 0.97 | CHRM3 (0.42) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621494-B1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | CHIESI FARM SPA (IT) | 2018-11-07 | — | — | EP | disclosed |
| US-20180133161-A1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-05-17 | — | — | US | disclosed |
| EP-3055069-B1 | PROCESS FOR PREPARING PHARMACEUTICAL FORMULATIONS FOR INHALATION COMPRISING A HIGH-DOSAGE STRENGTH ACTIVE INGREDIENT | CHIESI FARM SPA (IT) | 2017-12-06 | — | — | EP | disclosed |
| US-20150320691-A1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-11-12 | — | — | US | disclosed |
| EP-2621494-A1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | Chiesi Farmaceutici S.p.A. (IT) | 2013-08-07 | — | — | EP | disclosed |
| US-8440690-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-8440690-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-8404712-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-03-26 | — | — | US | disclosed |
| US-8404712-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-03-26 | — | — | US | disclosed |
| WO-2012052297-A1 | CARBONATE DERIVATIVES FOR THE TREATMENT OF COUGH | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-04-26 | — | — | WO | disclosed |
| US-20110319444-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | US | disclosed |
| US-8039483-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-10-18 | — | — | US | disclosed |
| US-8039483-B2 | Quinuclidine carbonate salts and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-10-18 | — | — | US | disclosed |
| EP-2313404-A1 | QUINUCLIDINE CARBONATE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.p.A. (IT) | 2011-04-27 | — | — | EP | disclosed |
| EP-2154136-A1 | Quinuclidine carbonate derivatives and medicinal compositions thereof | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-02-17 | — | — | EP | disclosed |
| EP-2154136-A1 | Quinuclidine carbonate derivatives and medicinal compositions thereof | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-02-17 | — | — | EP | disclosed |
| WO-2010015324-A1 | QUINUCLIDINE CARBONATE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015324-A1 | QUINUCLIDINE CARBONATE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | WO | disclosed |
| US-20100035922-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | US | disclosed |
| US-20100035922-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320691-A1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | SCD, SPTSSB, SCD5 | CHRM3 462/4885CHRM2 243/4885CHRM1 1007/4885 |
| US-20100035922-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHRM3, CHRM2, CHRM4 | CHRM3 1/4885CHRM2 2/4885CHRM1 4/4885 |
| US-20110319444-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHRM3, CHRM2, CHRM4 | CHRM3 1/4885CHRM2 2/4885CHRM1 4/4885 |
| US-20180133161-A1 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION | SCD, SPTSSB, SCD5 | CHRM3 462/4885CHRM2 243/4885CHRM1 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.