SCHEMBL22891759

SCHEMBL22891759

CC(C)(O)C(C)(C)OBc1ccc2c(c1)c1cc(Cl)ccc1n2-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PPARG P37231 3/20 0.37
MAT2A P31153 6/20 0.35
EDNRA P25101 1/20 0.35
PLK4 O00444 1/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
AURKB Q96GD4 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HCRTR1 O43613 1/20 0.34
MAPT P10636 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
FGFR1 P11362 1/20 0.33
POLB P06746 1/20 0.33
PRMT5 O14744 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767449 0.89 KDM4E (0.45) MEN1LMNAKMT2AL3MBTL1PPARG
SCHEMBL23510398 0.84 KDM4E (0.40) MEN1KMT2AL3MBTL1PPARGKDM4E
SCHEMBL12153426 0.83 ALDH1A1 (0.34) MEN1KMT2AL3MBTL1KDM4ECASP1
SCHEMBL24065233 0.83 KDM4E (0.38) KMT2AL3MBTL1PPARGEDNRAKDM4E
SCHEMBL16425015 0.82 KDM4E (0.45) MEN1LMNAKMT2AL3MBTL1PPARG
SCHEMBL22738639 0.81 KDM4E (0.36) MEN1LMNAKMT2AL3MBTL1PPARG
SCHEMBL16985652 0.81 KDM4E (0.33) MEN1KMT2AL3MBTL1EDNRAKDM4E
SCHEMBL22738615 0.80 MAPT (0.41) MEN1LMNAKMT2AL3MBTL1PPARG
SCHEMBL22541714 0.79 PPARG (0.32) MEN1KMT2AL3MBTL1PPARGKDM4E
SCHEMBL22021297 0.79 KDM4E (0.39) MEN1KMT2AL3MBTL1PPARGEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3763750-B1 POLYMER, MONOMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2023-07-19 EP disclosed
EP-3763750-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2021-01-13 EP disclosed