Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572196 | 0.76 | DPP7 (0.44) | KCNH2 | |
| SCHEMBL19547052 | 0.75 | HRH4 (0.30) | — | |
| SCHEMBL17284509 | 0.74 | KCNH2 (0.40) | KCNH2AKT1HSP90AA1HSP90AB1 | |
| SCHEMBL22837828 | 0.74 | KCNH2 (0.40) | KCNH2AKT1HSP90AA1HSP90AB1 | |
| SCHEMBL2760188 | 0.74 | SMN1; SMN2 (0.42) | KCNH2CARM1PRMT6 | |
| SCHEMBL19501771 | 0.74 | KCNH2 (0.40) | KCNH2AKT1HSP90AA1HSP90AB1 | |
| SCHEMBL8488055 | 0.74 | KCNH2 (0.40) | KCNH2AKT1HSP90AA1HSP90AB1 | |
| SCHEMBL25042763 | 0.74 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL549384 | 0.74 | — | — | |
| SCHEMBL1142602 | 0.74 | KCNH2 (0.52) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004482-A1 | SUBSTITUTED PYRAZOLOQUINAZOLONE COMPOUND AND APPLICATION THEREOF | 上海瑛派药业有限公司 | 2021-01-14 | — | — | WO | disclosed |