Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 2/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28609226 | 0.98 | PARP1 (0.77) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2487811 | 0.89 | PARP1 (1.00) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL57038 | 0.89 | PARP1 (1.00) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9413391 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29038784 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL28640108 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29157626 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9681519 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29255681 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29038783 | 0.87 | PARP1 (0.95) | PARP1NPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104920448-B | Naphthalimide potassium phosphate plant growth regulator and application thereof | 青岛科技大学 | 2017-05-03 | — | — | CN | claimed |
| CN-104920448-A | Naphthalimide potassium phosphate plant growth regulator and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-09-23 | — | — | CN | claimed |
| CN-104920448-B | Naphthalimide potassium phosphate plant growth regulator and application thereof | 青岛科技大学 | 2017-05-03 | — | — | CN | disclosed |
| US-9631219-B2 | Metabolic rate indicator for cellular populations | NALCO COMPANY (US) | 2017-04-25 | — | — | US | disclosed |
| CN-105646347-A | Naphthalimide aryl urea compound and application thereof | 青岛科技大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104920448-A | Naphthalimide potassium phosphate plant growth regulator and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-09-23 | — | — | CN | disclosed |
| WO-2011106363-A2 | METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS | NALCO COMPANY (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110207111-A1 | METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS | ECOLAB USA INC. | 2011-08-25 | — | — | US | disclosed |