SCHEMBL22893252

SCHEMBL22893252

O=C1C2=CCCC=C2C(=O)C1=C1Nc2ccccc2C=C1O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12387838 0.83 MAPT (0.41) GAAMAPT
SCHEMBL22893207 0.77 MAPT (0.47) GAAMAPT
SCHEMBL270508 0.66 MAPT (0.52) GAAMAPT
SCHEMBL9693452 0.63 GAA (0.39) GAAMAPT
SCHEMBL24005237 0.61 MAOA (0.45) MAPT
SCHEMBL8734161 0.59 GAA (0.36) GAAMAPT
SCHEMBL4621390 0.59 CDC25B (0.55) MAPT
SCHEMBL5210927 0.57 GAA (0.36) GAAMAPT
SCHEMBL7915886 0.56 GAA (0.35) GAAMAPT
SCHEMBL269763 0.56 MAPT (0.68) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3327488-B1 OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION ESSILOR INT (FR) 2021-01-06 EP disclosed