Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20560999 | 0.83 | — | — | |
| SCHEMBL239490 | 0.81 | ALDH1A1 (0.45) | KDM4ERECQLALDH1A1TSHR | |
| SCHEMBL21900667 | 0.79 | CYP2C19 (0.38) | TSHR | |
| SCHEMBL816642 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1965268 | 0.78 | ALDH1A1 (0.43) | KDM4ERECQLALDH1A1TSHR | |
| SCHEMBL23564290 | 0.77 | KDM4E (0.36) | KDM4ERECQLALDH1A1TSHR | |
| SCHEMBL31474633 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL10962985 | 0.76 | KDM4E (0.47) | KDM4ERECQLALDH1A1TSHR | |
| SCHEMBL5933120 | 0.76 | KDM4E (0.47) | KDM4ERECQLALDH1A1TSHR | |
| SCHEMBL3369011 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954202-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | ABBVIE INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20210009542-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | ABBVIE INC. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10954202-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | PTPN1, PTPN2, PTPN18 | KDM4E 2069/4885RECQL 2781/4885ALDH1A1 3671/4885 |
| US-20210009542-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PTPN1, PTPN2, PTPN18 | KDM4E 2069/4885RECQL 2781/4885ALDH1A1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.