Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25695763 | 0.93 | KDM5A (0.41) | KDM5AKDM4CKCNH2MGLLPHF8 | |
| SCHEMBL27384175 | 0.88 | KDM5A (0.39) | KDM5AKDM4CKCNH2MGLLPHF8 | |
| SCHEMBL22585241 | 0.88 | KDM5A (0.45) | KDM5AKDM4CMGLLPHF8CA12 | |
| SCHEMBL24113609 | 0.84 | KDM5A (0.42) | KDM5AKDM4CMGLLPHF8CA12 | |
| SCHEMBL24696839 | 0.84 | KDM5A (0.39) | KDM5AKDM4CKCNH2PHF8PAOX | |
| SCHEMBL24113607 | 0.84 | KDM5A (0.42) | KDM5AKDM4CMGLLPHF8CA12 | |
| SCHEMBL24444640 | 0.83 | KDM5A (0.45) | KDM5AKDM4CPHF8CES2CES1 | |
| SCHEMBL20854575 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL20854578 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL25341537 | 0.82 | KCNH2 (0.57) | KCNH2MGLLDNM1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007278-A1 | IMPROVED MRNA-LOADED LIPID NANOPARTICLES AND PROCESSES OF MAKING THE SAME | TRANSLATE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |