Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16531973 | 0.94 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL16531971 | 0.87 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL16532006 | 0.86 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL16531984 | 0.80 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL16532108 | 0.80 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL16532104 | 0.80 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL17907385 | 0.79 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL16531975 | 0.79 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL16531994 | 0.79 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL17907361 | 0.78 | DGAT1 (0.47) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042907-B1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | QUINGDAO HUANGHAI PHARMACEUTICAL CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |