Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894700 | 0.91 | CXCR4 (0.70) | CXCR4TDP1BCHESLC40A1CHRM1 | |
| SCHEMBL2084037 | 0.83 | CXCR4 (1.00) | CXCR4BCHECHRM1 | |
| SCHEMBL22894681 | 0.82 | CXCR4 (0.72) | CXCR4TDP1BCHESLC40A1LMNA | |
| SCHEMBL22894644 | 0.79 | CXCR4 (0.53) | CXCR4TDP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2085503 | 0.78 | CXCR4 (0.66) | CXCR4BCHESLC40A1LMNANPC1 | |
| SCHEMBL22894617 | 0.77 | CXCR4 (0.65) | CXCR4TDP1BCHELMNANPC1 | |
| SCHEMBL5556775 | 0.76 | CXCR4 (0.63) | CXCR4TDP1BCHEKDM4ELMNA | |
| SCHEMBL22894642 | 0.75 | CXCR4 (0.69) | CXCR4KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2084028 | 0.74 | CXCR4 (0.61) | CXCR4BCHESLC40A1 | |
| Hydrochloric Acid SCHEMBL711745 | 0.73 | BCHE (0.59) | CXCR4TDP1BCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009557-A1 | ACYCLIC CXCR4 INHIBITORS AND USES THEREOF | X4 PHARMACEUTICALS, INC. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009557-A1 | ACYCLIC CXCR4 INHIBITORS AND USES THEREOF | CXCR4, CXCR3, CXCR1 | CXCR4 1/4885TDP1 3777/4885BCHE 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.