Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583589 | 0.81 | LMNA (0.44) | LMNATSHRPTPN1CDC25BAKT1 | |
| SCHEMBL31297874 | 0.79 | LMNA (0.43) | LMNATSHRPTPN1CDC25BAKT1 | |
| SCHEMBL22897363 | 0.79 | TSHR (0.40) | LMNATSHRALDH1A1PTPN1CDC25B | |
| SCHEMBL28503112 | 0.77 | TSHR (0.38) | LMNATSHRALDH1A1PTPN1CDC25B | |
| SCHEMBL22897354 | 0.76 | TSHR (0.37) | LMNATSHRALDH1A1PTPN1CDC25B | |
| SCHEMBL31037231 | 0.76 | TSHR (0.37) | LMNATSHRALDH1A1PTPN1CDC25B | |
| SCHEMBL21017443 | 0.76 | TSHR (0.47) | LMNATSHRALDH1A1BCHEACHE | |
| SCHEMBL21017022 | 0.76 | TSHR (0.47) | LMNATSHRALDH1A1BCHEACHE | |
| SCHEMBL22897357 | 0.75 | TSHR (0.36) | LMNATSHRALDH1A1PTPN1CDC25B | |
| SCHEMBL22906585 | 0.75 | TSHR (0.36) | LMNATSHRALDH1A1PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239398-B | Dimethylcyclobutanone compound, dimethylcyclobutane compound and preparation methods thereof | 信越化学工业株式会社 | 2024-07-30 | — | — | CN | disclosed |
| EP-3766862-A1 | DIMETHYLCYCLOBUTANONE COMPOUNDS, DIMETHYLCYCLOBUTANE COMPOUNDS, AND PROCESSES FOR PREPARING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-01-20 | — | — | EP | disclosed |