Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926083 | 0.81 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL29620927 | 0.81 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL16030261 | 0.78 | NOTUM (0.41) | TDP1MAOB | |
| SCHEMBL22925925 | 0.77 | MAPT (0.40) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL29559433 | 0.77 | MAPT (0.40) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL18579433 | 0.77 | KDM4E (0.39) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL18579335 | 0.77 | LMNA (0.40) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL28733791 | 0.75 | KMT2A (0.43) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL22925831 | 0.74 | HDAC4 (0.49) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL29620876 | 0.74 | HDAC4 (0.49) | MAPTKDM4ESMN1; SMN2ALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |