Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | RHOC | P08134 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22897508 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HTTMAPTPKM | |
| SCHEMBL29559840 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HTTMAPTPKM | |
| SCHEMBL22897989 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HTTMAPTHPGD | |
| SCHEMBL22897833 | 0.83 | HTT (0.44) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL22897841 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL22897926 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HTTMAPTPKM | |
| SCHEMBL22897909 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HTTMAPTPKM | |
| SCHEMBL22897993 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HTTMAPTCYP2D6 | |
| SCHEMBL29559380 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HTTMAPTCYP2D6 | |
| SCHEMBL28679416 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HTTMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |