SCHEMBL22898041

SCHEMBL22898041

O=[N+]([O-])c1cc(Cl)ccc1COCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
PDE7A Q13946 3/20 0.47
PDE7B Q9NP56 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KIF18A Q8NI77 1/20 0.46
PIN1 Q13526 2/20 0.45
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.42
APP P05067 1/20 0.42
VCAM1 P19320 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28394155 0.89 MAPK1 (0.52) CYP1A2CYP3A4HPGDCYP2C19NPC1
SCHEMBL22898034 0.89 MEN1 (0.47) CYP1A2CYP3A4HPGDCYP2C19NPC1
SCHEMBL19622954 0.84 CYP1A2 (0.54) CYP1A2CYP3A4CYP2C19NPC1RAB9A
SCHEMBL22898025 0.83 NPC1 (0.48) CYP1A2CYP3A4HPGDCYP2C19NPC1
SCHEMBL22897914 0.83 TSHR (0.43) NPC1RAB9APIN1TSHRMEN1
SCHEMBL22898040 0.82 ALDH1A1 (0.53) HPGDNPC1RAB9APIN1TSHR
SCHEMBL22898046 0.80 MAPT (0.48) CYP1A2CYP3A4HPGDCYP2C19NPC1
SCHEMBL7640891 0.79 CYP1A2 (0.49) CYP1A2CYP3A4HPGDCYP2C19NPC1
SCHEMBL4879420 0.78 POLB (0.57) CYP1A2CYP3A4HPGDCYP2C19PIN1
SCHEMBL7060448 0.78 NPC1 (0.49) CYP1A2CYP3A4HPGDCYP2C19NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed