Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 16/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22898693 | 0.93 | ITGAL (0.40) | ITGALITGB2ICAM1ELANE | |
| SCHEMBL22898494 | 0.93 | ITGAL (0.40) | ITGALITGB2ICAM1ELANE | |
| SCHEMBL22898513 | 0.88 | ITGAL (0.38) | ITGALITGB2ICAM1 | |
| SCHEMBL22898526 | 0.88 | ITGAL (0.38) | ITGALITGB2ICAM1 | |
| SCHEMBL22898581 | 0.86 | ITGAL (0.43) | ITGALITGB2ICAM1ELANETSHR | |
| SCHEMBL22898568 | 0.84 | ITGAL (0.42) | ITGALITGB2ICAM1ELANE | |
| SCHEMBL22898566 | 0.79 | ITGAL (0.39) | ITGALITGB2ICAM1ELANE | |
| SCHEMBL22898503 | 0.78 | ITGAL (0.43) | ITGALITGB2ICAM1ELANETSHR | |
| SCHEMBL22898548 | 0.78 | ITGAL (0.43) | ITGALITGB2ICAM1ELANETSHR | |
| SCHEMBL17347153 | 0.78 | ITGAL (0.43) | ITGALITGB2ICAM1ELANETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154941-B1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2021-01-20 | — | — | EP | disclosed |