Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PRKDC | P78527 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038146 | 0.87 | CYP1A2 (0.49) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL5424277 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL29975509 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL21816699 | 0.86 | MAPT (0.45) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL28016967 | 0.85 | POLB (0.58) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL27185292 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL2540530 | 0.85 | MAPT (0.49) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL14660718 | 0.85 | POLB (0.58) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL7980589 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 | |
| SCHEMBL3273374 | 0.85 | MAPT (0.47) | ALDH1A1MAPTPRKDCKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7070096-A | — | — | None | — | — | JP | disclosed |
| JP-7089959-A | — | — | None | — | — | JP | disclosed |
| US-11802129-B1 | Pyrido[3,4-b]indol-1-one compounds as anticancer agents | King Faisal University (SA) | 2023-10-31 | — | — | US | disclosed |
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | SPERMATECH AS (NO) | 2023-08-24 | — | — | US | disclosed |
| EP-3634962-B1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-05-24 | — | — | EP | disclosed |
| US-20210371417-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2021-12-02 | — | — | US | disclosed |
| US-11111243-B2 | Azaindole compounds as histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| EP-3634962-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| CN-110997671-A | Azaindole compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-107325002-B | Method for synthesizing aryl halide by taking aryl carboxylic acid as raw material | 南昌大学 | 2020-03-27 | — | — | CN | disclosed |
| US-6140328-A | FOR TREATING TUMOR | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1042294-A1 | HETEROCYCLIC CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031067-A1 | HETEROCYCLIC CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-06-24 | — | — | WO | disclosed |
| US-5872243-A | Caged nucleotides | MOLECULAR PROBES, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5556961-A | Nucleosides with 5'-O-photolabile protecting groups | AFFYMETRIX, INC. | 1996-09-17 | — | — | US | disclosed |
| JP-H0789959-A | NOVEL CHEMICAL LUMINESCENT COMPOUND | DOUJIN KAGAKU KENKYUSHO:KK | 1995-04-04 | — | — | JP | disclosed |
| JP-H0770096-A | FLUORESCENT LABELING AGENT CONTAINING BENZO-1,3-THIAZOLE SKELETON | DOUJIN KAGAKU KENKYUSHO:KK | 1995-03-14 | — | — | JP | disclosed |
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11111243-B2 | Azaindole compounds as histone methyltransferase inhibitors | EHMT2, EHMT1, EZH2 | ALDH1A1 1590/4885MAPT 3215/4885PRKDC 1168/4885 |
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | NR5A1, NR1I3, NR5A2 | ALDH1A1 1219/4885MAPT 4855/4885PRKDC 3382/4885 |
| US-20210371417-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | EHMT2, EHMT1, EZH2 | ALDH1A1 1590/4885MAPT 3215/4885PRKDC 1168/4885 |
| US-11802129-B1 | Pyrido[3,4-b]indol-1-one compounds as anticancer agents | IDO1, TYMP, AURKB | ALDH1A1 1148/4885MAPT 1042/4885PRKDC 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.