SCHEMBL228995

SCHEMBL228995

NC(=O)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10787567 0.95
SCHEMBL9660945 0.78
Urea SCHEMBL27464354 0.78
SCHEMBL10139 0.78
SCHEMBL28084851 0.78
SCHEMBL3691779 0.76 LDHA (0.43)
SCHEMBL3691782 0.76 LDHA (0.43)
Urea SCHEMBL4814143 0.74
Urea SCHEMBL11569843 0.74
Hydrochloric Acid SCHEMBL4395995 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749429-B1 3,5-DISUBSTITUTED AND 3,5,6-TRISUBSTITUTED 2-ISOXAZOLINES AND ISOXAZOLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS HOECHST AG (DE) 1999-06-30 EP claimed
EP-0638074-B1 ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE BASF AG (DE) 1999-03-31 EP claimed
US-5814627-A ANTIINFLAMMATORY AGENTS, ASTHMA; RHEUMATIC AND AUTOIMMUNE DISEASES; INHIBITORS OF LEUKOTRIENES, CYTOKINES, E.G. INTERLEUKINS, OXYGEN RADICALS AND PROTEASES HOECHST AKTIENEGESELLSCHAFT (DE) 1998-09-29 US claimed
EP-0490263-A1 Alpha-oxoacetamide derivatives SYNTEX (U.S.A.) INC. (US) 1992-06-17 EP claimed
EP-0054872-B1 3,4-DI-SUBSTITUTED 1,2,5-OXADIAZOLE-2 OXIDES, METHOD FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CASSELLA Aktiengesellschaft (DE) 1984-10-31 EP claimed
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 US disclosed
US-12404262-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-09-02 US disclosed
EP-4440701-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 EP disclosed
US-20230250248-A1 CATALYST-FREE SURFACE FUNCTIONALIZATION AND POLYMER GRAFTING ILLUMINA, INC. 2023-08-10 US disclosed
US-20230212148-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-07-06 US disclosed
WO-2023102523-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed
US-11618808-B2 Catalyst-free surface functionalization and polymer grafting ILLUMINA, INC. (US) 2023-04-04 US disclosed
US-4144345-A Dihydroxybenzisoxazolin-3-yl-substituted-5-nitroimidazoles as antibacterials and antiprotozoals MERCK & CO., INC. (US) 1979-03-13 US disclosed
US-4144047-A SOYBEANS MONSANTO COMPANY (US) 1979-03-13 US disclosed
US-4136180-A HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS PFIZER INC. (US) 1979-01-23 US disclosed
US-4129568-A 2-[3-Aryl-2-isoxazolin-5-yl]benzoates MONSANTO COMPANY (US) 1978-12-12 US disclosed
US-4080340-A Nitroimidazoles MERCK & CO., INC. (US) 1978-03-21 US disclosed
US-4062960-A Hypolipidemic alkenesulfonamides PFIZER INC. (US) 1977-12-13 US disclosed
US-4010176-A Isoxazole substituted nitroimidazoles MERCK & CO., INC. (US) 1977-03-01 US disclosed
US-3983107-A ARTERIOSCLEROSIS PFIZER INC. (US) 1976-09-28 US disclosed