Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.39 |
| ▸ | GRN | P28799 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990846 | 0.82 | ASPH (0.45) | HSD17B10TSHRLCKFYNCA12 | |
| SCHEMBL30018797 | 0.82 | ASPH (0.45) | HSD17B10TSHRLCKFYNCA12 | |
| SCHEMBL17943444 | 0.81 | SOS1 (0.38) | HSD17B10TSHRCA1CA2CA5A | |
| SCHEMBL30614604 | 0.80 | CSNK2A1 (0.44) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL1404736 | 0.79 | LCK (0.46) | HSD17B10LCKFYNCA12CA1 | |
| SCHEMBL25340523 | 0.79 | KDM4E (0.58) | KDM4ESORT1GRNGABRPGABRD | |
| Nitrous Acid SCHEMBL28850943 | 0.77 | ASPH (0.41) | HSD17B10TSHRLCKFYNCA12 | |
| SCHEMBL14901955 | 0.76 | HSD17B10 (0.44) | HSD17B10TSHRLCKFYNCA12 | |
| SCHEMBL20639017 | 0.75 | TSHR (0.40) | TSHRCA12CA1CA2CA3 | |
| SCHEMBL31697155 | 0.75 | TSHR (0.40) | TSHRCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745185-A | Imidazopyrimidines as EED inhibitors and use thereof | 密歇根大学董事会 | 2024-10-08 | — | — | CN | disclosed |
| CN-115212311-B | Pharmaceutical composition and application thereof | 苏州亚盛药业有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-114127073-B | Imidazopyrimidines as EED inhibitors and use thereof | 密歇根大学董事会 | 2024-05-31 | — | — | CN | disclosed |
| CN-115212311-A | Pharmaceutical composition and application thereof | 苏州亚盛药业有限公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-3999510-A1 | IMIDAZOPYRIMIDINES AS EED INHIBITORS AND THE USE THEREOF | The Regents Of The University Of Michigan (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114127073-A | Imidazopyrimidines as EED inhibitors and uses thereof | 美国密歇根州立大学试剂中心 | 2022-03-01 | — | — | CN | disclosed |
| WO-2021011713-A1 | IMIDAZOPYRIMIDINES AS EED INHIBITORS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-01-21 | — | — | WO | disclosed |