Sugi Predict

Sugi Predict / Targets / ASPH

ASPH

Aspartyl/asparaginyl beta-hydroxylase · Q12797 · ASPH on Sugi Atlas →

27,896 patent compounds predicted against ASPH, 21,869 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL547943 SCHEMBL547943 0.68 11/20
SCHEMBL517935 SCHEMBL517935 0.55 11/20
Enfenamic Acid Enfenamic Acid (SCHEMBL25191) 0.60 4/20
SCHEMBL231979 SCHEMBL231979 0.61 3/20
SCHEMBL222146 SCHEMBL222146 0.55 3/20
SCHEMBL70035 SCHEMBL70035 0.50 3/20
Water Water (SCHEMBL336347) 0.48 3/20
SCHEMBL155043 SCHEMBL155043 0.46 3/20
SCHEMBL232024 SCHEMBL232024 0.44 3/20
SCHEMBL290570 SCHEMBL290570 0.44 3/20
SCHEMBL474036 SCHEMBL474036 0.67 2/20
SCHEMBL65841 SCHEMBL65841 0.63 2/20
SCHEMBL163637 SCHEMBL163637 0.63 2/20
SCHEMBL127480 SCHEMBL127480 0.61 2/20
SCHEMBL175932 SCHEMBL175932 0.61 2/20
SCHEMBL232233 SCHEMBL232233 0.61 2/20
SCHEMBL101547 SCHEMBL101547 0.55 2/20
SCHEMBL130291 SCHEMBL130291 0.55 2/20
Quinolinic Acid Quinolinic Acid (SCHEMBL69230) 0.53 2/20
Quinolinic Acid Quinolinic Acid (SCHEMBL343618) 0.53 2/20

Clinical trials — most relevant to ASPH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Association of L-asparaginase-Methotrexate-Dexamethasone for Nasal and Nasal-type Natural Killer (NK)-T-cell Lymphoma PHASE2COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB PHASE2COMPLETED
Pharmacogenetics of Disulfiram for Cocaine PHASE2COMPLETED
The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy PHASE2NOT_YET_RECRUITING
Phase 1 Trial of PAN-301-1 (SNS-301) in Cancer Patients PHASE1COMPLETED
D-aspartate and Therapeutic Exercise EARLY_PHASE1UNKNOWN
Mutation Analysis of 17α-Hydroxylase nanUNKNOWN
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease nanUNKNOWN
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease nanNOT_YET_RECRUITING
Syndromes With Neonatal Salt Loss: Not Only Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency (21OH-ISC) nanRECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase. nanUNKNOWN
Biomarker for the Early Diagnosis and Monitoring in Tyrosinemia Type 1 (BioTyrosin) nanWITHDRAWN
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Replacement of Vitamin D in Patients With Active Tuberculosis nanCOMPLETED
Final Height in Patients With CAH nanUNKNOWN
Ovarian Reserve and Matrix Metalloproteinases nanCOMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery nanCOMPLETED
Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy nanUNKNOWN
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease nanUNKNOWN
Systemic Biomarkers of Brain Injury From Hyperammonemia nanRECRUITING
Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU) nanRECRUITING
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Circadian Rhythms and Sleep in Familial DSPS and ASPS nanCOMPLETED
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions nanRECRUITING
Identification of Acute Intermittent Porphyria Modifying Genes nanRECRUITING
Screening of Lysosomal Storage Disorders Diseases in Minority Groups nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ASPH binder may also engage these)

ProteinNameSimilarity
Q28056 — 1.000 Q28056 →
Q8BSY0 — 0.998 Q8BSY0 →
Q28034 — 0.987 Q28034 →
Q10651 — 0.987 Q10651 →
P52194 — 0.986 P52194 →
DHX29 ATP-dependent RNA helicase DHX29 0.985 landscape →
O18738 — 0.985 O18738 →
P48193 — 0.985 P48193 →
P34652 — 0.985 P34652 →
Q5QQ54 — 0.985 Q5QQ54 →
Q60432 — 0.984 Q60432 →
C3XRY1 — 0.984 C3XRY1 →
B4GUZ2 — 0.984 B4GUZ2 →
Q24276 — 0.984 Q24276 →
A5E032 — 0.984 A5E032 →
P08478 — 0.984 P08478 →
KDM5B Lysine-specific demethylase 5B 0.984 landscape →
O61307 — 0.984 O61307 →
Q8W4J3 — 0.984 Q8W4J3 →
Q9TSZ6 — 0.984 Q9TSZ6 →
Q58CP9 — 0.984 Q58CP9 →
EPB41 Protein 4.1 0.984 landscape →
P84903 — 0.984 P84903 →
KAT8 Histone acetyltransferase KAT8 0.984 landscape →
O54774 — 0.984 O54774 →
Q24740 — 0.983 Q24740 →
Q28685 — 0.983 Q28685 →
SMARCC2 SWI/SNF complex subunit SMARCC2 0.983 landscape →
O43150 — 0.983 O43150 →
A8X181 — 0.983 A8X181 →