Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.47 |
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297913 | 0.85 | RXFP1 (0.51) | KDM4EHIF1AALDH1A1GAAHPGD | |
| SCHEMBL17082363 | 0.84 | CCR1 (0.47) | KDM4EHIF1AALDH1A1HPGDRXFP1 | |
| SCHEMBL22900543 | 0.84 | CCR1 (0.52) | KDM4EHIF1AALDH1A1HPGDMAPT | |
| SCHEMBL466458 | 0.83 | QPCT (0.85) | QPCT | |
| SCHEMBL29410511 | 0.83 | QPCT (0.85) | QPCT | |
| SCHEMBL3820969 | 0.82 | CCR1 (0.46) | QPCTKDM4EHIF1AALDH1A1GAA | |
| SCHEMBL3811905 | 0.82 | QPCT (0.56) | QPCTKDM4EHIF1AALDH1A1HPGD | |
| SCHEMBL4296944 | 0.82 | CCR1 (0.55) | KDM4EHIF1AALDH1A1HPGDRXFP1 | |
| SCHEMBL22900296 | 0.81 | QPCT (0.53) | QPCTKDM4EHIF1AALDH1A1GAA | |
| SCHEMBL22900215 | 0.81 | QPCT (0.59) | QPCTHIF1AMAPTRXFP1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |