Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900291 | 0.81 | QPCT (0.60) | QPCTKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL466458 | 0.77 | QPCT (0.85) | QPCT | |
| SCHEMBL29410511 | 0.77 | QPCT (0.85) | QPCT | |
| SCHEMBL466495 | 0.75 | QPCT (0.72) | QPCT | |
| SCHEMBL22900359 | 0.75 | QPCT (0.46) | QPCTKDM4EPOLBGAAALDH1A1 | |
| SCHEMBL22900609 | 0.74 | QPCT (0.47) | QPCTKDM4EPOLBGAAALDH1A1 | |
| SCHEMBL22900345 | 0.71 | QPCT (0.58) | QPCTGAAALDH1A1MAPTMAPK1 | |
| SCHEMBL4297913 | 0.66 | RXFP1 (0.51) | KDM4EGAAALDH1A1KMT2AMAPT | |
| SCHEMBL17082363 | 0.65 | CCR1 (0.47) | KDM4EALDH1A1KMT2AMEN1HIF1A | |
| SCHEMBL1444457 | 0.64 | QPCT (0.86) | QPCTKDM4EPOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |