Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | SIK1 | P57059 | 1/20 | 0.30 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.30 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900166 | 0.81 | QPCT (0.51) | QPCTNMT1 | |
| SCHEMBL22900418 | 0.81 | QPCT (0.36) | QPCT | |
| SCHEMBL22900514 | 0.72 | BRD3 (0.43) | QPCT | |
| SCHEMBL22900475 | 0.71 | BRD3 (0.37) | — | |
| SCHEMBL22900473 | 0.70 | BRD3 (0.35) | — | |
| SCHEMBL22900354 | 0.68 | BRD4 (0.38) | QPCT | |
| SCHEMBL22900256 | 0.67 | QPCT (0.54) | QPCT | |
| SCHEMBL22900456 | 0.64 | QPCT (0.51) | QPCT | |
| SCHEMBL22900540 | 0.63 | BRD4 (0.42) | QPCT | |
| SCHEMBL22900276 | 0.58 | NMT1 (0.41) | QPCTNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |