Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158730 | 0.89 | PDE4D (0.59) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL16453474 | 0.77 | KDM4C (0.53) | PDE4DKDM4EPOLBHCAR2KDR | |
| SCHEMBL15555140 | 0.73 | KDM4E (0.51) | PDE4DKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL7814443 | 0.73 | PDE4D (0.58) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL10862602 | 0.73 | KDM4E (0.51) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL31367819 | 0.73 | PDE4D (0.73) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL10860621 | 0.73 | KDM4E (0.51) | PDE4DKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL23757849 | 0.71 | KDM4E (0.50) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL9025212 | 0.71 | HCAR2 (0.66) | PDE4DKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL3078972 | 0.71 | PDE4D (0.56) | PDE4DKDM4EPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |