Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 16/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900251 | 0.84 | QPCT (0.54) | QPCTTP53SMN1; SMN2 | |
| SCHEMBL22900287 | 0.83 | QPCT (0.58) | QPCT | |
| SCHEMBL22900516 | 0.83 | QPCT (0.52) | QPCTTP53 | |
| SCHEMBL22900208 | 0.81 | QPCT (0.54) | QPCT | |
| SCHEMBL22900343 | 0.81 | QPCT (0.53) | QPCT | |
| SCHEMBL22900288 | 0.80 | QPCT (0.52) | QPCTBACE1IDH1 | |
| SCHEMBL22900524 | 0.80 | QPCT (0.52) | QPCT | |
| SCHEMBL22900292 | 0.79 | QPCT (0.55) | QPCT | |
| SCHEMBL22900224 | 0.79 | QPCT (0.48) | QPCTTP53SMN1; SMN2 | |
| SCHEMBL22900221 | 0.79 | QPCT (0.53) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |