Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.41 |
| ▸ | RAB9A | P51151 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29224227 | 0.99 | NPC1 (0.40) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL22524619 | 0.90 | BRD4 (0.36) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29224350 | 0.89 | BRD4 (0.36) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22900721 | 0.85 | NPC1 (0.38) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL5952134 | 0.83 | FGFR1 (0.41) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL25427962 | 0.82 | FGFR1 (0.40) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL20401102 | 0.82 | MAPT (0.55) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL1271910 | 0.82 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31450920 | 0.82 | SMN1; SMN2 (0.38) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL5953456 | 0.82 | DGAT1 (0.40) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139859-A | Benzimidazole and azabenzimidazole IL-17 inhibitor compounds | 詹森药业有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118119613-A | Benzimidazoles as IL-17 modulators | 詹森药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |