Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900292 | 0.89 | QPCT (0.55) | QPCTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL22900241 | 0.83 | QPCT (0.53) | QPCT | |
| SCHEMBL22900350 | 0.82 | QPCT (0.55) | QPCTKDM4EGAAALOX15 | |
| SCHEMBL22900526 | 0.81 | QPCT (0.54) | QPCTALDH1A1HPGDKDM4E | |
| SCHEMBL22900342 | 0.81 | QPCT (0.54) | QPCT | |
| SCHEMBL22900575 | 0.81 | QPCT (0.54) | QPCT | |
| SCHEMBL4300306 | 0.80 | ALDH1A1 (0.53) | QPCTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL16053682 | 0.79 | QPCT (0.88) | QPCT | |
| SCHEMBL17476410 | 0.79 | QPCT (0.88) | QPCT | |
| SCHEMBL29410458 | 0.79 | QPCT (0.88) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |