SCHEMBL22901565 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	1/20	0.47

▸	HTT	P42858	1/20	0.47

▸	SMN1; SMN2	Q16637	1/20	0.47

▸	MAOB	P27338	7/20	0.47

▸	HTR1A	P08908	3/20	0.43

▸	DRD2	P14416	3/20	0.43

▸	ABCB1	P08183	2/20	0.43

▸	NPC1	O15118	1/20	0.42

▸	RAB9A	P51151	1/20	0.42

▸	MRGPRX4	Q96LA9	1/20	0.40

▸	GCK	P35557	1/20	0.40

▸	APP	P05067	1/20	0.40

▸	SLC2A1	P11166	1/20	0.39

▸	SLC2A4	P14672	1/20	0.39

▸	IDO1	P14902	1/20	0.39

▸	AGXT	P21549	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22901542	0.96	MAPT (0.47)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901579	0.94	MAPT (0.46)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901577	0.93	MAOB (0.46)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901549	0.92	MAPT (0.48)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901581	0.91	MAPT (0.45)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901571	0.90	MAPT (0.48)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901554	0.90	MAPT (0.51)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901551	0.87	MAPT (0.46)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901548	0.86	MAPT (0.45)	MAPTHTTSMN1; SMN2MAOBHTR1A
SCHEMBL22901563	0.85	MAOB (0.49)	MAPTHTTSMN1; SMN2MAOBHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021008588-A1	CLASS OF PYRIMIDINE QUINOLINE DERIVATIVES AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF	广州新民培林医药科技有限公司	2021-01-21	—	—	WO	disclosed