SCHEMBL22901959

SCHEMBL22901959

C[C@H]1C[C@H]2[C@@H](CC(=O)N1)C2(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.38
CREBBP Q92793 3/20 0.38
EP300 Q09472 1/20 0.38
CRBN Q96SW2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22902081 1.00 BRD4 (0.38) BRD4CREBBPEP300CRBN
SCHEMBL7536500 0.72
SCHEMBL9306449 0.72
SCHEMBL20614486 0.72 CREBBP (0.52) BRD4CREBBPEP300CRBN
SCHEMBL25838829 0.69
SCHEMBL357257 0.69
SCHEMBL12160740 0.69
SCHEMBL16274298 0.68 CES2 (0.34) CRBN
SCHEMBL16274311 0.68 CES2 (0.34) CRBN
SCHEMBL11273146 0.68 CES2 (0.34) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12152107-B2 Isomer-enriched 3-caranlactams and polyamides based thereon with high optical purity and adjustable crystallinity for high-performance applications Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-11-26 US disclosed
US-20210017332-A1 ISOMER-ENRICHED 3-CARANLACTAMS AND POLYAMIDES BASED THEREON WITH HIGH OPTICAL PURITY AND ADJUSTABLE CRYSTALLINITY FOR HIGH-PERFORMANCE APPLICATIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-01-21 US disclosed
US-20210017332-A1 ISOMER-ENRICHED 3-CARANLACTAMS AND POLYAMIDES BASED THEREON WITH HIGH OPTICAL PURITY AND ADJUSTABLE CRYSTALLINITY FOR HIGH-PERFORMANCE APPLICATIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017332-A1 ISOMER-ENRICHED 3-CARANLACTAMS AND POLYAMIDES BASED THEREON WITH HIGH OPTICAL PURITY AND ADJUSTABLE CRYSTALLINITY FOR HIGH-PERFORMANCE APPLICATIONS NOTUM, MGAM, CARM1 BRD4 3989/4885CREBBP 2307/4885EP300 3182/4885
US-12152107-B2 Isomer-enriched 3-caranlactams and polyamides based thereon with high optical purity and adjustable crystallinity for high-performance applications NOTUM, MGAM, CARM1 BRD4 3989/4885CREBBP 2307/4885EP300 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.