Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706960 | 0.89 | MEN1 (0.38) | MEN1KMT2APOLBKDM4ELMNA | |
| SCHEMBL24751429 | 0.85 | MAPT (0.36) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL6128461 | 0.84 | MEN1 (0.39) | MEN1KMT2APOLBKDM4ELMNA | |
| SCHEMBL20198527 | 0.83 | MEN1 (0.37) | MEN1KMT2APOLBKDM4ELMNA | |
| SCHEMBL21416438 | 0.83 | PDK2 (0.32) | — | |
| SCHEMBL25061350 | 0.82 | PDK2 (0.30) | — | |
| SCHEMBL22182136 | 0.81 | — | — | |
| SCHEMBL20755611 | 0.80 | PDK2 (0.32) | — | |
| SCHEMBL18801298 | 0.80 | ALDH1A1 (0.31) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL26532061 | 0.79 | MAPT (0.35) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826079-B1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |