Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.88 |
| ▸ | BTK | Q06187 | 8/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18665658 | 0.94 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665570 | 0.91 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665605 | 0.91 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665626 | 0.91 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL21316391 | 0.91 | EGFR (0.98) | EGFRBTK | |
| SCHEMBL24861920 | 0.90 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18666042 | 0.90 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL29886839 | 0.90 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665587 | 0.90 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665590 | 0.90 | EGFR (1.00) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |