⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025527 | 0.79 | PNMT (0.62) | — | |
| SCHEMBL6571988 | 0.79 | TAAR1 (0.67) | — | |
| SCHEMBL1538555 | 0.78 | HSPA5 (0.45) | — | |
| SCHEMBL29712515 | 0.78 | HSPA5 (0.45) | — | |
| SCHEMBL29519238 | 0.77 | IDO1 (0.62) | — | |
| SCHEMBL6740216 | 0.77 | TAAR1 (0.71) | — | |
| SCHEMBL672407 | 0.77 | IDO1 (0.62) | — | |
| SCHEMBL29118641 | 0.74 | PNMT (0.44) | — | |
| SCHEMBL126469 | 0.74 | — | — | |
| SCHEMBL4771885 | 0.74 | TAAR1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020116596-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITION FOR FORMING FILM AND PRODUCTION METHOD FOR ORGANOPOLYSILOXANE CURED PRODUCT FILM | ダウ・東レ株式会社 | 2020-06-11 | — | — | WO | claimed |
| CN-118119626-A | Fused bicyclic heteroaryl compounds useful as NLRP3 inhibitors | 豪夫迈·罗氏有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2020116596-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITION FOR FORMING FILM AND PRODUCTION METHOD FOR ORGANOPOLYSILOXANE CURED PRODUCT FILM | ダウ・東レ株式会社 | 2020-06-11 | — | — | WO | disclosed |
| CN-109748885-A | A kind of preparation method of Ceritinib intermediate and Ceritinib | 新发药业有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109665984-A | Synthetic method of 2-substituted indole compound | 南京工业大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-107488098-B | A kind of continuous producing method of preparation of industrialization 2,3- difluoro-benzotrifluorides, 3,4- difluorobenzonilyiles | 淄博飞源化工有限公司 | 2018-07-27 | — | — | CN | disclosed |
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| CN-107488098-A | A kind of difluoro-benzotrifluoride of preparation of industrialization 2,3, the continuous producing method of 3,4 difluorobenzonilyiles | 淄博飞源化工有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-106488920-A | The preparation method of antiviral compound | 吉利德制药有限责任公司 | 2017-03-08 | — | — | CN | disclosed |
| EP-1663204-B1 | C-KIT MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-1799727-A2 | LOW FOULING AND HIGH ACTIVITY POLYMERIZATION PROCESS | ExxonMobil Chemical Patents Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006009949-A2 | LOW FOULING AND HIGH ACTIVITY POLYMERIZATION PROCESS | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| EP-1159314-B1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEM CO (US) | 2004-08-04 | — | — | EP | disclosed |
| CN-1138793-C | Process for producing polyethylene | �Ϻ���ͨ��ѧ | 2004-02-18 | — | — | CN | disclosed |
| US-6534613-B2 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | EASTMAN CHEMICAL COMPANY | 2003-03-18 | — | — | US | disclosed |
| CN-1332753-A | Process for producing polyethylene | EASTMAN CHEM CO (US) | 2002-01-23 | — | — | CN | disclosed |
| US-20020007024-A1 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | WESTLAKE LONGVIEW CORPORATION | 2002-01-17 | — | — | US | disclosed |
| EP-1159314-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052067-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| US-4798818-A | ALUMINUM FLUORIDE, TRANSITION METAL COMPOUND, HYDROGEN FLUORIDE | DOW CORNING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |