SCHEMBL2290595

SCHEMBL2290595

C=C[Si](O)(Cc1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
TSHR P16473 2/20 0.34
MAOB P27338 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CALM1 P0DP23 1/20 0.32
GAA P10253 1/20 0.32
IDO1 P14902 2/20 0.31
THRB P10828 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
AKR1B1 P15121 1/20 0.31
MAPK1 P28482 1/20 0.31
MMP9 P14780 1/20 0.31
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288347 0.78 MAPT (0.34) NR1H2NR1H3TSHRALDH1A1
SCHEMBL2295123 0.77 TSHR (0.39) NR1H2NR1H3TSHRMAOBTDP1
SCHEMBL15302819 0.77 TSHR (0.39) NR1H2NR1H3TSHRMAOBTDP1
SCHEMBL8761998 0.77 TSHR (0.39) NR1H2NR1H3TSHRMAOBTDP1
SCHEMBL6905785 0.76 TSHR (0.42) NR1H2NR1H3TSHRMAOBTDP1
SCHEMBL2292618 0.74 MAPT (0.33) NR1H2NR1H3GAA
SCHEMBL2294978 0.73 NR1H2 (0.38) NR1H2NR1H3TSHRMAOBTDP1
SCHEMBL2292298 0.73 NR1H2 (0.35) NR1H2NR1H3TSHRMAOBADH1B
SCHEMBL2291148 0.72 PCSK9 (0.34) NR1H2NR1H3TSHRTDP1CES2
SCHEMBL3126057 0.72 MAOB (0.40) TSHRMAOBADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US claimed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US claimed
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US disclosed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US disclosed