SCHEMBL2292298

SCHEMBL2292298

C=CC[Si](O)(Cc1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
GAA P10253 1/20 0.33
MMP9 P14780 1/20 0.33
TSHR P16473 2/20 0.32
MAOB P27338 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
CYP2C19 P33261 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CALM1 P0DP23 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15302725 0.86 ALDH1A1 (0.34) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL2292460 0.79 NR1H2 (0.33) NR1H2NR1H3TSHRCYP2C19ALDH1A1
SCHEMBL27912803 0.79 HTT (0.33) NR1H2NR1H3TSHRCYP2C19ALDH1A1
SCHEMBL8762346 0.79 CES2 (0.37) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL2290902 0.79 GAA (0.36) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL15302578 0.79 GAA (0.36) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL2291119 0.76 GAA (0.33) NR1H2NR1H3GAAALDH1A1
SCHEMBL2286891 0.76 NR1H2 (0.39) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL15302531 0.75 MMP9 (0.38) NR1H2NR1H3GAAMMP9TSHR
SCHEMBL6841673 0.74 ALDH1A1 (0.34) NR1H2NR1H3MMP9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US claimed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US claimed
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US disclosed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US disclosed