Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.75 |
| ▸ | IGF2R | P11717 | 4/20 | 0.56 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.53 |
| ▸ | UMPS | P11172 | 4/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19442388 | 1.00 | FBP1 (0.75) | FBP1IGF2RAMDHD2UMPSATIC | |
| SCHEMBL14948801 | 1.00 | FBP1 (0.75) | FBP1IGF2RAMDHD2UMPSATIC | |
| SCHEMBL18464493 | 1.00 | FBP1 (0.75) | FBP1IGF2RAMDHD2UMPSATIC | |
| SCHEMBL16502555 | 0.87 | FBP1 (0.57) | FBP1IGF2RAMDHD2 | |
| SCHEMBL16502638 | 0.87 | FBP1 (0.57) | FBP1IGF2RAMDHD2 | |
| SCHEMBL24454421 | 0.86 | FBP1 (0.56) | FBP1IGF2R | |
| SCHEMBL30189347 | 0.86 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSATIC | |
| SCHEMBL20154711 | 0.86 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSATIC | |
| SCHEMBL19321572 | 0.85 | FBP1 (0.54) | FBP1IGF2RAMDHD2DNPH1 | |
| SCHEMBL18289603 | 0.85 | FBP1 (0.54) | FBP1IGF2RAMDHD2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020006423-A9 | SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO | EDITAS MEDICINE, INC. (US) | 2021-01-21 | — | — | WO | disclosed |