Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084636 | 0.91 | LMNA (0.36) | MAPTTP53LMNANR1I2CASR | |
| SCHEMBL22906232 | 0.90 | MAPT (0.33) | MAPTTP53LMNANR1I2CASR | |
| SCHEMBL22031854 | 0.90 | CYP1A2 (0.38) | MAPTTP53LMNANR1I2CASR | |
| SCHEMBL22031792 | 0.88 | CASR (0.40) | MAPTTP53LMNANR1I2CASR | |
| SCHEMBL22085782 | 0.87 | MAPT (0.37) | MAPTLMNAPOLBKMT2ASLC22A12 | |
| SCHEMBL22084637 | 0.86 | POLB (0.35) | MAPTLMNAPOLB | |
| SCHEMBL22906297 | 0.86 | LMNA (0.40) | MAPTLMNANR1I2CASRKMT2A | |
| SCHEMBL25200988 | 0.85 | PTGDR2 (0.36) | MAPTFPR2PROKR1 | |
| SCHEMBL22085783 | 0.85 | AR (0.36) | MAPT | |
| SCHEMBL30389092 | 0.85 | PTGDR2 (0.36) | MAPTFPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555563-B | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118108674-A | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118084803-A | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084802-A | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114555563-A | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3999494-A2 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| WO-2021009334-A2 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |