Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048023 | 1.00 | SLC6A4 (0.35) | SLC6A4SLC6A3KDM4EDRD2DRD4 | |
| SCHEMBL21048022 | 1.00 | SLC6A4 (0.35) | SLC6A4SLC6A3KDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL16600519 | 0.98 | SLC6A4 (0.34) | SLC6A4SLC6A3KDM4EDRD2DRD4 | |
| SCHEMBL4756581 | 0.87 | — | — | |
| SCHEMBL1678939 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL5395481 | 0.84 | — | — | |
| SCHEMBL3273602 | 0.81 | DRD2 (0.36) | KDM4EDRD2DRD4DRD3 | |
| SCHEMBL10102970 | 0.81 | DRD2 (0.36) | KDM4EDRD2DRD4DRD3 | |
| SCHEMBL14303972 | 0.81 | KDM4E (0.39) | KDM4E | |
| SCHEMBL20160971 | 0.79 | KDM4E (0.35) | SLC6A4SLC6A3KDM4EDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011868-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |