Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 9/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | ATR | Q13535 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 6/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120731 | 0.87 | TBK1 (0.43) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL29547748 | 0.87 | TBK1 (0.43) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20120729 | 0.87 | TBK1 (0.43) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20128900 | 0.87 | TBK1 (0.43) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20120325 | 0.84 | MAPT (0.42) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20128901 | 0.84 | MAPT (0.42) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20120327 | 0.84 | MAPT (0.42) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL29547540 | 0.84 | MAPT (0.42) | ATMMTORATRPIK3CAMAPT | |
| SCHEMBL20128893 | 0.82 | TBK1 (0.44) | CYP4F2 | |
| SCHEMBL20128890 | 0.79 | MAPT (0.42) | ATMMTORATRPIK3CAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |