Demannose

Demannose

SCHEMBL2290731

O=C[C@H](O)[C@@H](O)[C@@H](O)C(O)CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 1/20 0.55
PDE4A P27815 1/20 0.46
AKR1B1 P15121 1/20 0.43
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
MPI P34949 1/20 0.35
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TOP1 P11387 1/20 0.33
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL1051912 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL14486320 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL15321015 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL525084 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20956808 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL20500378 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL14958551 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL6529193 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Demannose SCHEMBL13947310 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1
Galactose SCHEMBL20818999 1.00 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7993884-B2 Beta-xylosidase for conversion of plant cell wall carbohydrates to simple sugars THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2011-08-09 US disclosed
US-20090280541-A1 Beta-xylosidase for conversion of plant cell wall carbohydrates to simple sugars THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2009-11-12 US disclosed